ea0029oc13.3 | Adrenal Basic | ICEECE2012
Louiset E.
, Duparc C.
, Young J.
, Boutelet I.
, Renouf S.
, Bram Z.
, Groussin L.
, Caron P.
, Tabarin A.
, Grunenberger F.
, Christin-Maitre S.
, Kuhn J.
, Anouar Y.
, Bertherat J.
, Lefebvre H.
Illicit expression of membrane receptors for circulating regulatory factors, such as gastric inhibitory polypeptide (GIP), luteinizing hormone (LH) and serotonin (5-HT) receptors, has been well documented in ACTH-independent macronodular adrenal hyperplasias (AIMAHs) causing Cushings syndrome. In addition, we have observed an abnormal expression of ACTH in some steroidogenic cells in two AIMAH tissues. The aim of the present study was to investigate the role of local pro...